| 1 |  Anna Kiesenhofer (AUT) | | 3:52:45 |
| 2 |  Annemiek Van Vleuten (NED) | Movistar Team | 1:15 |
| 3 |  Elisa Longo Borghini (ITA) | Trek - Segafredo | 1:29 |
| 4 |  Lotte Kopecky (BEL) | Liv Racing | 1:39 |
| 5 | Marianne Vos (NED) | Jumbo - Visma | 1:46 |
| 6 |  Lisa Brennauer (GER) | Ceratizit - Wnt | s.t. |
| 7 |  Coryn Labecki (USA) | Team Dsm | s.t. |
| 8 | Marta Cavalli (ITA) | Fdj - Nouvelle Aquitaine - Futuroscope | s.t. |
| 9 |  Olga Zabelinskaya (UZB) | | s.t. |
| 10 |  Cecilie Uttrup Ludwig (DEN) | Fdj - Nouvelle Aquitaine - Futuroscope | s.t. |
| 11 |  Elizabeth Deignan-Armitstead (GBR) | Trek - Segafredo | s.t. |
| 12 |  Margarita Victoria García Cañellas (SPA) | Alé - Btc Ljubljana | s.t. |
| 13 |  Ashleigh Moolman Pasio (RSA) | Team SD Worx | s.t. |
| 14 |  Katarzyna Niewiadoma (POL) | Canyon - Sram Racing | s.t. |
| 15 | Anna van der Breggen (NED) | Team SD Worx | s.t. |
| 16 |  Karol-Ann Canuel (CAN) | Team SD Worx | 2:20 |
| 17 |  Alena Amialyusik (BLR) | Canyon - Sram Racing | s.t. |
| 18 | Marta Lach (POL) | Ceratizit - Wnt | 2:28 |
| 19 |  Eugenia Bujak (SLO) | Alé - Btc Ljubljana | s.t. |
| 20 |  Christine Majerus (LUX) | Team SD Worx | s.t. |
| 21 |  Eri Yonamine (JPN) | Team Tibco - Silicon Valley Bank | s.t. |
| 22 |  Paula Andrea Patiño Bedoya (COL) | Movistar Team | 2:30 |
| 23 | Liane Lippert (GER) | Team Dsm | 2:32 |
| 24 |  Omer Shapira (ISR) | Canyon - Sram Racing | 2:38 |
| 25 | Demi Vollering (NED) | Team SD Worx | 2:56 |
| 26 |  Tiffany Cromwell (AUS) | Canyon - Sram Racing | s.t. |
| 27 | Anna Plichta (POL) | Lotto - Soudal Ladies | 3:13 |
| 28 | Ane Santesteban González (SPA) | Team Bikeexchange | 3:19 |
| 29 | Leah Thomas (USA) | Movistar Team | 3:22 |
| 30 |  Juliette Labous (FRA) | Team Dsm | s.t. |
| 31 | Chloé Dygert-Owen (USA) | Canyon - Sram Racing | 6:06 |
| 32 | Alison Jackson (CAN) | Liv Racing | 7:02 |
| 33 |  Tereza Neumanová (CZE) | Women Cycling Sport | s.t. |
| 34 |  Arlenis Sierra Cañadilla (CUB) | A.r. Monex Women's Pro Cycling Team | s.t. |
| 35 |  Rasa Leleivyte (LTU) | Aromitalia - Basso Bikes - Vaiano | s.t. |
| 36 | Leah Kirchmann (CAN) | Team Dsm | s.t. |
| 37 |  Katrine Aalerud (NOR) | Movistar Team | 7:07 |
| 38 |  Ah-reum Na (KOR) | | 8:23 |
| 39 |  Tamara Dronova-Balabolina (RUS) | | s.t. |
| 40 | Sarah Gigante (AUS) | | s.t. |
| 41 | Hannah Ludwig (GER) | Canyon - Sram Racing | s.t. |
| 42 | Julie Van De Velde (BEL) | Jumbo - Visma | s.t. |
| 43 | Hiromi Kaneko (JPN) | | s.t. |
| 44 | Marta Bastianelli (ITA) | Alé - Btc Ljubljana | 9:31 |
| 45 | Ruth Edwards (Winder) (USA) | Trek - Segafredo | s.t. |
| 46 |  Marlen Reusser (SWI) | Alé - Btc Ljubljana | s.t. |
| 47 | Grace Brown (AUS) | Team Bikeexchange | s.t. |
| 48 | Soraya Paladin (ITA) | Liv Racing | 15:55 |
| DNF |  Vera Looser-Adrian (NAM) | | - |
| DNF | Trixi Worrack (GER) | Trek - Segafredo | - |
| DNF |  Teniel Campbell (TRI) | Team Bikeexchange | - |
| DNF |  Lizbeth Yareli Salazar Vázquez (MEX) | A.r. Monex Women's Pro Cycling Team | - |
| DNF | Anna Shackley (GBR) | Team SD Worx | - |
| DNF |  Antri Christoforou (CYP) | Women Cycling Sport | - |
| DNF |  Selam Amha Gerefiel (ETH) | Wcc Team | - |
| DNF | Carla Oberholzer (RSA) | | - |
| DNF |  Jiajun Sun (CHN) | | - |
| DNF |  Mossana Debesai (ERA) | | - |
| DNF | Emma Cecilie Norsgaard Jørgensen (DEN) | Movistar Team | - |
| DNF |  Valeriya Kononenko (UKR) | | - |
| DNF |  Agua Marina Espínola Salinas (PAR) | Massi - Tactic | - |
| DNF |  Maria José Vargas Barrientos (CRC) | A.r. Monex Women's Pro Cycling Team | - |
| DNF | Valerie Demey (BEL) | Liv Racing | - |
| DNF |  Jutatip Maneephan (THA) | | - |
| DNF | Amanda Spratt (AUS) | Team Bikeexchange | - |
| DNF |  Catalina Anais Soto Campos (CHI) | Nxtg Racing | - |
| DNF | Stine Anderson Borgli (NOR) | Fdj - Nouvelle Aquitaine - Futuroscope | - |
